Vinitha Ganesan, PhD

Precision Medicine Initiative for Commercialization (PreMIC) Program Manager

Leads the commercial translation in precision medicine in collaboration with the Institute for Precision Medicine (IPM).

Development Operations Manager

Globin Solutions Inc

Leads the operational processes, including the regulatory process and Investigational New Drug Application (IND) to the FDA.

Education and Experience

Vinitha brings a strong background in proteomics, genomics and immunology to her work at sciVelo. Vinitha was a consultant at Fourth River Solutions, a non-profit consulting group run by STEM professionals, using academic acumen to solve real-world business problems. In her PhD program at Carnegie Mellon University, Vinitha was trained in proteomics and developed a new reagent and improved methods for discovering biomarkers using immunoproteomics. This led to the establishment of collaborations in academia resulting in proteomics studies in a number of diseases, as well as commercial translation of the research done at Minden lab, Carnegie Mellon University. Vinitha is passionate about wellness and co-founded a university-wide program called YesPlus at Carnegie Mellon University to provide stress management tools for the community.

Education

PhD, Biological Sciences, Carnegie Mellon University, 2017
M.Tech, Biotechnology, Anna University, 2012
B.Tech, Industrial Biotechnology, Anna University, 2010

Research Experience

Graduate Student Researcher, Department of Biological Sciences, Carnegie Mellon University
Advisor: Jonathan Minden, PhD
  • Ganesan, V. & Ascherman, D. P. Citrullinated Autoantigen Targets as Markers of Extra-Articular Disease in Rheumatoid Arthritis. Protein Deimination in Human Health and Disease 191–203 (Springer International Publishing, 2017). doi: 10.1007/978-3-319-58244-3_11.
  • Ganesan, V., Ascherman, D.P., Minden, J.S. Immunoproteomics technologies in the discovery of autoantigens in autoimmune diseases, Biomolecular Concepts (2016). doi: 10.1515/bmc-2016-0007
  • Ganesan, V., Schmidt, B., Avula, R., Cooke, D., Maggiacomo, T., Tellin, L., Ascherman, D.P., Bruchez, M.P., and Minden, J.S. Immuno-proteomics: Development of a novel reagent for separating antibodies from their target proteins. Biochim Biophys Acta (2015). doi:10.1016/j.bbapap.2014.10.011
  • Van, P.T., Ganesan, V., Bass, V., Parthasarathy, A., Schlesinger, D., Minden, J.S. In-gel equilibration for improved protein retention in 2DE-based proteomic workflows. Electrophoresis (2014). doi:10.1002/elps.201400256
  • Yablonska S, Ganesan V, Ferrando LM, Kim J, Pyzel A, Baranova OV, Khattar NK, Larkin TM, Baranov SV, Chen N, Strohlein CE, Stevens DA, Wang X, Chang YF, Schurdak ME, Carlisle DL, Minden JS, Friedlander RM. Mutant huntingtin disrupts mitochondrial proteostasis by interacting with TIM23. Proc Natl Acad Sci U S A. 2019 Aug 13;116(33):16593-16602. doi: 10.1073/pnas.1904101116.
  • Blundon M, Ganesan V, Redler B, Van PT, Minden JS. Two-Dimensional Difference Gel Electrophoresis. Methods Mol Biol. 2019;1855:229-247. doi: 10.1007/978-1-4939-8793-1_20.

  • Graduate Research Fellow, CSIR – Institute of Genomics and Integrative Biology
    Advisor: Kausik Chakraborty, PhD
  • Studied unfolded protein stress response (UPR) pathway in budding yeast using Phage Display Library sequencing.
  • Studied cell-to-cell variation in the UPR signaling in budding yeast using flow cytometry.

  • Undergraduate Researcher, Anna University, India
    Advisors: Dr. P Kaliraj and Dr. S Meenakshisundaram
  • Purified a vaccine target protein for filariasis to help develop antibodies.
  • Extracted biochemical components from Prosopis juliflora leaves to identify an eco-friendly mosquito larvicide.
  • Commercial Translation Experience

    Graduate Student Researcher, Department of Biological Sciences, Carnegie Mellon University
  • Synthesized a commercializable biotech tool.
  • Performed customer discovery for commercial projects.

  • Consultant, Fourth River Solutions
  • Conducted secondary market research and revenue analysis for the biotech tools industry.
  •  
    Share