Drew Bradshaw – sciVelo

Junior Commercial Translation Architect

Develop strategies to commercialize projects within sciVelo’s digital health and precision medicine themes

Graduate Research Fellow

Studying mechanisms underlying how cancers respond to the tumor microenvironment using microphysiological systems and systems biology to uncover therapeutic treatments for metastatic disease

sciVelo Translator - University of Pittsburgh

Education and Experience

Drew is currently a graduate research fellow in Cellular and Molecular Pathology and is working on his thesis in Dr. Alan Wells’ laboratory. His work focuses on understanding the link between therapeutically stressed cancer secretomes and resistance in tumor microenvironments (TME). This work pays special attention to the non-malignant cell populations, with investigations into pathological changes in extracellular matrix (ECM) as a driver of progression and cancer persistence. This work utilizes novel microphysiomimetic systems to develop all-human TMEs from human organs. Prior to his matriculation, Drew has worked at the University of Pennsylvania in Dr. Dennis Discher’s Molecular and Biophysics laboratory. During this time, he also consulted with the Wharton affiliated, Penn Biotechnology Group, which aimed to develop commercialization strategies for early stage projects. Drew also worked with Corning Incorporated to construct new life science products and applications which were commercialized as market available products and solutions. These earlier experiences and enthusiasm for developing market-focused solutions led Drew to sciVelo and the Center for Commercial Applications of Healthcare Data team.

Education

PhD Candidate, Cellular and Molecular Pathology, University of Pittsburgh, Expected Winter 2019
BS, Biological Sciences, Ithaca College, 2010

Research Experience

Wells A., Clark A., Bradshaw, AM., Ma B., & Edington H. (2019). The great escape: How metastases of melanoma, and other carcinomas, avoid elimination. Exp. Biol. and Med. 243(17–18), 1245–1255.

Bradshaw AM., Sylakowski K., Wells, A. (2018). The Pro-reparative Engine: Stem Cells Aid Healing by Dampening Inflammation. Curr. Pathobiol. Rep. 6: 109.

Dingal PCDP., Bradshaw AM., Cho S., Raab M., Buxboim A., Swift J., Discher DE. (2015). Minimal matrix model with scar-like heterogeneity reveals a mechano-sensitive repressor in stem cell plasticity. Nature Materials; 9: 951-60.

Sosale NG., Rouhiparkouhi T., Bradshaw AM., Dimova R., Lipowsky R., Discher DE. (2014) Cell Rigidity and Shape Override CD47’s ‘Self’ signaling in Phagocytosis by Hyperactivating Myosin-II. Blood; 125(3): 542-52.

Li G., Bradshaw AM., Lai F., Liu A. (2013). Yeast Cell Assay with a Surface Plasmon Resonance Sensor at Multiple Penetration Depths. J Microbiol Methods; 95(2): 223-8.

Bradshaw AM., Salt M., Bell A., Zeitler M., Litra N., Smith AM. (2011). Cross-linking by protein oxidation in the rapidly setting gel-based glues of slugs. J Exp Biol. 214:1699-706.

Below are the three areas you need to edit in order to place a new staff profile on the homepage, in the staff profile landing page, and the full staff bio page. These instructions are hidden and will not show up on the public profile page. You can, however, delete this box when you no longer need these instructions. I - Create a new Staff Profile page 1. Go to Posts and click "Add New" 2. Enter the person’s full name and degrees in the “Enter Title Here” field 3. Scroll down to the Muffin Builder section 4. Click on "Templates" 5. Select: "New Staff Profile Template" 6. Select: "REPLACE current builder content" 7. Click: "Use Template" 8. Update content within each Item accordingly. Anything within (parenthesizes) should be updated. 9. Scroll to the LAYOUT section and choose the following options to maintain the appearance of the page and navigation: a. Switch "Hide The Content" button to ON b. For Layout, choose "Right Sidebar" c. For Sidebar, select "Meet Our Translators" 10. Under Categories, choose the appropriate staff role. 11. Click Publish when finished. II - Add new Offer to appear on "Meet the Team" on homepage 1. Under "Offer", click "Add New" 2. Enter the person’s full name in the “Enter Title Here” field. 3. Copy/paste the content from the Body Copy area of another offer into this offer and update accordingly. This will guarantee you get the same look and feel. 4. Choose the appropriate category based on job title. 5. Add the person’s headshot under “Featured Image” and make sure the background is transparent (.png) 6. Update the Post Attribute Order field to keep with the alphabetical order. You will need to view the list of offers to determine the appropriate Order attribute to assign. You will then need to update all the subsequent offers so they continue with the appropriate order. 7. Hit Publish. III - Add new profile to Meet the Team landing page This content will need to be added manually and does not pull from other areas on the site, like the homepage or staff profile pages. You'll need to copy/paste the following code into the appropriate area and update it with the new staff member's information. Stage location: http://stage.scivelo.pitt.edu/meet-our-translators/ Production location: http://scivelo.pitt.edu/meet-our-translators/

Megan Breski, MS

Clinical and Translational Science Institute Program Manager