Drew Bradshaw

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Junior Commercial Translation Architect

Develop strategies to commercialize projects within sciVelo’s digital health and precision medicine themes

Graduate Research Fellow

Studying mechanisms underlying how cancers respond to the tumor microenvironment using microphysiological systems and systems biology to uncover therapeutic treatments for metastatic disease
sciVelo Translator - University of Pittsburgh

Education and Experience

Drew is currently a graduate research fellow in Cellular and Molecular Pathology and is working on his thesis in Dr. Alan Wells’ laboratory. His work focuses on understanding the link between therapeutically stressed cancer secretomes and resistance in tumor microenvironments (TME). This work pays special attention to the non-malignant cell populations, with investigations into pathological changes in extracellular matrix (ECM) as a driver of progression and cancer persistence. This work utilizes novel microphysiomimetic systems to develop all-human TMEs from human organs. Prior to his matriculation, Drew has worked at the University of Pennsylvania in Dr. Dennis Discher’s Molecular and Biophysics laboratory. During this time, he also consulted with the Wharton affiliated, Penn Biotechnology Group, which aimed to develop commercialization strategies for early stage projects. Drew also worked with Corning Incorporated to construct new life science products and applications which were commercialized as market available products and solutions. These earlier experiences and enthusiasm for developing market-focused solutions led Drew to sciVelo and the Center for Commercial Applications of Healthcare Data team.

Education

PhD Candidate, Cellular and Molecular Pathology, University of Pittsburgh, Expected Winter 2019
BS, Biological Sciences, Ithaca College, 2010

Research Experience

  • Wells A., Clark A., Bradshaw, AM., Ma B., & Edington H. (2019). The great escape: How metastases of melanoma, and other carcinomas, avoid elimination. Exp. Biol. and Med. 243(17–18), 1245–1255.
  • Bradshaw AM., Sylakowski K., Wells, A. (2018). The Pro-reparative Engine: Stem Cells Aid Healing by Dampening Inflammation. Curr. Pathobiol. Rep. 6: 109.
  • Dingal PCDP., Bradshaw AM., Cho S., Raab M., Buxboim A., Swift J., Discher DE. (2015). Minimal matrix model with scar-like heterogeneity reveals a mechano-sensitive repressor in stem cell plasticity. Nature Materials; 9: 951-60.
  • Sosale NG., Rouhiparkouhi T., Bradshaw AM., Dimova R., Lipowsky R., Discher DE. (2014) Cell Rigidity and Shape Override CD47’s ‘Self’ signaling in Phagocytosis by Hyperactivating Myosin-II. Blood; 125(3): 542-52.
  • Li G., Bradshaw AM., Lai F., Liu A. (2013). Yeast Cell Assay with a Surface Plasmon Resonance Sensor at Multiple Penetration Depths. J Microbiol Methods; 95(2): 223-8.
  • Bradshaw AM., Salt M., Bell A., Zeitler M., Litra N., Smith AM. (2011). Cross-linking by protein oxidation in the rapidly setting gel-based glues of slugs. J Exp Biol. 214:1699-706.
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    Megan Breski

    Megan Breski, MS

    Clinical and Translational Science Institute Program Manager

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