Ayantika (Annie) Ghosh, PhD, MS

Anyankita Ghosh

Commercial Translational Architect

Pediatric technology development in collaboration with Children’s Hospital of Pittsburgh of UPMC and the McGowan Institute for Regenerative Medicine

Research Associate

Department of Surgery
University of Pittsburgh

Modeling alpha-1 antitrypsin deficiency disease in immunocompromised mice transplanted with human hepatocytes; drug discovery studies in induced pluripotent stem cell derived hepatocytes.

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Education & Experience


PhD, Biochemistry, Bose Institute, Calcutta, India 2009
MS, Biochemistry, University of Calcutta, India, 2002
BS, Chemistry, Sambalpur University, India, 2000

Research Experience

Post-Doctoral Research

Research Associate, Department of Surgery

Led independent studies on molecular modeling of alpha1-antitrypsin deficiency disease in immunocompromised mice by repopulating their livers with human hepatocytes and treatment with human specific AAV virus expressing the mutant allele of alpha-1 antitrypsin.

Postdoctoral Research Scholar, Department of Pediatrics-Gastroenterology & Hepatology

Successfully led and completed research projects on molecular signaling pathways implicated in inflammatory bowel disease and intra-hepatic Cholestasic disease.

Graduate Research
Studied Cell death signaling pathways in acetaminophen induced liver damage.

Undergraduate Research
Contributing member of an international research group to identify and develop a vaccine for a virulent strain of cholera virus that was later submitted to World Health Organization (WHO).

Commercial Translation Experience

Commercial Translation Architect

Help University of Pittsburgh investigators reach their commercial translational goals by facilitating and aligning shared incentives, solution scopes and resources between Pitt and industry.

University of Pittsburgh Technology Transfer Office (Innovation Institute), Pittsburgh, PA
Licensing Associate Intern                                                                                                                           

  • Reviewed and evaluated the commercial potential of inventions, conducted prior art searches and created technology assessment reports for life science and medical device inventions.
  • Performed competitive market assessment of various current and upcoming products related to the inventions.
  • Developed strategic plans and recommendations for licensing opportunity.

Pittsburgh Life Science Greenhouse, Pittsburgh, PA
Market Research Analyst Intern

  • Conducted secondary market research and strategy evaluation for the US $9.8 billion chronic liver disease market and studied its impact on US healthcare.
  • Performed competitive analysis of various current and upcoming hepatitis and liver cancer management strategies in the US market and designed a product portfolio analysis to identify current market trends.